Ozoralizumab Antibody

SKU: orb1980322

Description

Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.Ozoralizumab binds human serum albumin and can be used to study rheumatoid arthritis.

Research Area

Cell Biology

Images & Validation

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Key Properties

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CAS Number	1167985-17-2
MW	38.44 kDa
Purity	95.6% (SEC-HPLC)
Target	TNF

Bioactivity

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In Vivo

METHODS: Tg197 mice were injected Subcutaneously with 1 mg/kg dose of Ozoralizumab (ATN-103) twice weekly to evaluat the formation of ADA against Each anti-TNFα antibody an the effect of long-term administration of these anti-TNFα antibodies on TNFα-mediated TNFα in Tg197 mice. Efficacy of polyarthritis. Results: Ozoralizumab (ATN-103) significantly and comparably reduced arthritis scores.

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Disclaimer	For research use only

Alternative Names

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ATN-103, TNF-α, TS-152

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Gene Symbol

TNF

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