p38α inhibitor 6

SKU: orb3028194

Description

p38α inhibitor6 (compound 19) is a p38α inhibitor with an IC50 value of 0.68 μM. It induces apoptosis, arrests the cell cycle in the G0 and G2/M phases, reduces TNF-α concentration, upregulates the expression of the tumor suppressor gene p53, increases the Bax/BCL-2 ratio, and activates caspase3/7.

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Key Properties

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Target	p38 MAPK,Caspase,MDM-2/p53,Bcl-2 Family,Apoptosis

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

p38 MAPK,Caspase,MDM-2/p53,Bcl-2 Family,Apoptosis

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