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PDE4-IN-18

SKU: orb2664113

Description

PDE4-IN-18 (compound 1l) is a PDE4 inhibitor with an IC50 value of 1.55 μM and exhibits anti-inflammatory activity. It mitigates inflammation by reducing excessive infiltration of immune cells and enthesial formation, as well as decreasing the mRNA expression of pro-inflammatory cytokines (such as TNF-α and IL-6) in the synovial tissues. PDE4-IN-18 is suitable for research into rheumatoid arthritis and psoriasis.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research

Images & Validation

Key Properties

TargetInterleukin,PDE,TNF

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

PDE4-IN-18 (orb2664113)

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