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PDE4B-IN-4

SKU: orb3027936

Description

PDE4B-IN-4 is an inhibitor of PDE4B (IC50: 2.82 nM) and TNF-α (IC50: 7.20 nM). It demonstrates anti-inflammatory properties by reducing neutrophilia in a mouse model of lipopolysaccharide (LPS)-induced sepsis.

Images & Validation

Key Properties

MW489.52
FormulaC26H27N5O5
SMILESO=C1NC(N/N=C/C2=CC=C(OC)C(OC)=C2)=NC(C3=CC(OC4CCCC4)=C(OC)C=C3)=C1C#N
TargetPDE,TNF

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

PDE4B-IN-4 (orb3027936)

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