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Platycodin D2

SKU: orb1297236

Description

Platycodin D2 is a saponin adjuvant with reduced hemolytic activity. It enhances both cellular and humoral immune responses to antigens like hepatitis B surface antigen in murine models, safely promoting a balanced Th1 and Th2 profile. This makes it a valuable tool for vaccine adjuvant research in immunology.

Research Area

Immunology & Inflammation, Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number66663-90-9
MW1387.46
Purity99.92% (May vary between batches)
FormulaC63H102O33
SMILES[H][C@@]1(O[C@H]2[C@H](O)CO[C@@]([H])(O[C@H]3[C@H](C)O[C@@]([H])(O[C@@H]4[C@@H](O)[C@@H](O)CO[C@H]4OC(=O)[C@]45CCC(C)(C)C[C@@]4([H])C4=CC[C@]6([H])[C@@]7(C)C[C@H](O)[C@H](O[C@]8([H])O[C@H](CO)[C@@H](O)[C@H](O[C@]9([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@H]8O)C(CO)(CO)[C@]7([H])CC[C@@]6(C)[C@]4(C)C[C@H]5O)[C@H](O)[C@@H]3O)[C@@H]2O)OC[C@](O)(CO)[C@H]1O
TargetIL Receptor,HBV
SolubilityDMSO:100 mg/mL (72.07 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (2.88 mM)

Bioactivity

Target IC50
Proliferation:4 - 18 microg/mL(ED50)
In Vitro
A novel triterpenoid saponin, deapioplatycoside E (1) was isolated from the root extract of Platycodon grandiflorum, together with the seven known saponins 2 - 8, i. e., platycoside E (2), deapioplatycodin D3 (3), platycodin D3 (4), polygalacin D2 (5), Platycodin D2 (6), deapioplatycodin D (7) and platycodin D (8). The structure of the new saponin 1 was determined on the basis of spectral analysis and chemical evidence

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Platycodin D 2, Platycodin D2, Platycodin D-2, inhibit, Inhibitor, HBV, ILReceptor, IL receptor, IL Receptor
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Platycodin D2 (orb1297236)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
¥ 1,170.00
5 mg
¥ 2,080.00
10 mg
¥ 2,990.00
1 ml x 10 mM (in DMSO)
¥ 4,290.00
25 mg
¥ 4,680.00
50 mg
¥ 6,760.00
100 mg
¥ 9,490.00
DispatchUsually dispatched within 3-5 working days
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