PPARα/δ agonist 3

SKU: orb2944725

Description

PPARα/δ agonist 3 (Compound 8) is an orally active PPAR agonist capable of activating PPARα, PPARδ, and PPARγ, with EC50 values of 5.6 nM, 3.4 nM, and 1278 nM, respectively. It exhibits anti-cholestatic activity in mouse models of cholestatic liver disease induced by ANIT or CDCA.

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Key Properties

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CAS Number	3050611-33-8
MW	450.451
Formula	C₂₃H₂₅F₃N₂O₄
SMILES	O=C(O)C(OC=1C(=CC(=CC1C)CN2C(=O)N(C3=CC=C(C=C3)C(F)(F)F)CC2)C)(C)C
Target	PPAR

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

PPAR

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