PPARγ/δ modulator 2

SKU: orb2945693

Description

PPARγ/δ modulator 2 (Compound 3h) functions as a PPARγ agonist and a PPARδ antagonist, with Ki values for PPARγ and PPARδ of 2.8 μM and 43 nM, respectively. It significantly enhances adiponectin production and promotes adipogenic differentiation in human bone marrow-derived mesenchymal stem cells (hBM-MSCs). This compound is applicable in research on metabolic diseases related to hypoadiponectinemia.

Images & Validation

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Key Properties

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MW	564.67
Formula	C₁₇H₁₇ClIN₅O₂Se
SMILES	C1[C@@H](C([C@@H]([Se]1)CN2C=NC3=C(N=C(N=C32)Cl)NCC4=CC(=CC=C4)I)O)O
Target	PPAR

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

PPAR

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