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PROTAC HDAC6 degrader 1

SKU: orb1982407

Description

Compound A6 is a potent and selective PROTAC that degrades HDAC6 with a DC50 of 3.5 nM. This molecule induces apoptosis and shows notable antiproliferative activity in myeloid leukemia cell lines in vitro, supporting its investigation in oncology and hematology research.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2785404-76-2
MW734.8
FormulaC37H46N6O10
SMILESO=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2OCC(NCCCCCCCC(NC4=CC=C(C(NCCCCCCC(NO)=O)=O)C=C4)=O)=O
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information