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PROTAC HDAC6 degrader 2

SKU: orb2945241

Description

Compound 1 (PROTAC HDAC6 degrader 2) is a potent degrader of HDAC6 with an IC50 of 0.643 µM, inducing its ubiquitination and proteasomal degradation. This tool compound is utilized in cancer research, supporting in vitro and in vivo studies for both hematological malignancies and solid tumors.

Research Area

Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW733.678
FormulaC34H33F2N9O8
SMILESC1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCC(=O)NCC4=CC=CC(=C4)CNC5=NC=C(C=N5)C6=NN=C(O6)C(F)F
TargetPROTACs,HDAC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information