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R112

SKU: orb1304448

Description

R112

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

Key Properties

CAS Number575474-82-7
MW312.3
Purity99.06%
FormulaC16H13FN4O2
SMILESOc1cccc(Nc2ncc(F)c(Nc3cccc(O)c3)n2)c1
TargetSyk
SolubilityDMSO:55 mg/mL (176.11 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.4 mM)

Bioactivity

Target IC50
Syk:96 nM(Ki)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

tryptase, TNF-α, reversible, Spleen tyrosine kinase, Syk, R112, R-112, R 112, phosphorylation, LTC4, IL-8, inhibit, GM-CSF, Elafibranor, fast, Inhibitor, histamine, basophil, allergic rhinitis, (E)-Elafibranor

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Key Properties

No computed properties available.

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Protocol Information

R112 (orb1304448)

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% DMSO +
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% Tween 80 +
%

Available Sizes

Select a size below

1 mg
¥ 1,040.00
2 mg
¥ 1,170.00
5 mg
¥ 1,560.00
1 ml x 10 mM (in DMSO)
¥ 1,690.00
10 mg
¥ 2,210.00
25 mg
¥ 3,510.00
50 mg
¥ 5,070.00
100 mg
¥ 7,280.00
500 mg
¥ 14,560.00
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