Recombinant Human ICOS Protein

SKU: orb2994712

Description

Recombinant Human Inducible T-cell Costimulator is produced by our Mammalian expression system and the target gene encoding Glu21-Phe141 is expressed with a human IgG1 Fc tag at the C-terminus.

Research Area

Immunology & Inflammation

Images & Validation

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Key Properties

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Expression System	Human Cells
Biological Origin	Human
Biological Activity	BLI: Loaded Recombinant Human ICOSLG (C-6His) (Cat#orb2995052) on HIS1K Biosensor, can bind Recombinant Human ICOS (C-Fc) (Cat#orb2994712) with an affinity constant of 9.56 nM as determined in BLI assay. (Regularly tested)
Tag	C-Fc
Expression Region	Glu21-Phe141
Endotoxins	< 1 EU/µg as determined by LAL test.
Conjugation	Unconjugated
MW	Predicted: 40.9 KDa. Observed: 47 KDa, reducing conditions
Purity	SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.

Storage & Handling

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Storage	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Form/Appearance	Lyophilized
Buffer/Preservatives	0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Expiration Date	6 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Inducible T-cell costimulator;activation-inducible lymphocyte immunomediatory molecule; CD278; AILIM; CVID1;ICOS;

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