Research Grade Glofitamab Antibody

SKU: orb2978451

Description

GlofitamabisaT-cell-engagingbispecificantibodypossessinganovel2:1structurewithbivalencyforCD20onBcellsandmonovalencyforCD3onTcells.Glofitamabisaninvestigational,T-cellbispecificantibodywithadistinctivedesignthatfeatures2FabarmsforbindingCD20onBcells,alongwith1FabarmforbindingCD3onTcells.TheCD3bindingarmisfuseddirectlytooneoftheCD20-bindingarmsinahead-to-tailfashionviaashortflexiblelinker.

Images & Validation

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Tested Applications	ELISA, FA, FACS, In vivo
Reactivity	Human

Key Properties

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Antibody Type	Biosimilar Antibody
Host	Human Humanized
Clonality	Monoclonal
Isotype	IgG1-kappa-lambda
Source/Expression System	Mammalian Cells
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Endotoxin	Please contact with the lab for this information.
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Form/Appearance	Liquid
Buffer/Preservatives	0.01M PBS, pH 7.4.
Concentration	1.06mg/ml
Disclaimer	For research use only

Alternative Names

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Bispecific,CD20-TCB(2:1),RG-6026,CAS:2229047-91-8

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

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Protocol Information

FACS

Fluorescence-Activated Cell Sorting (FC, Flow cytometry)

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ELISA

Enzyme-linked Immunosorbent Assay (EIA)

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