Rhesus macaque ALK-7 Protein, His Tag (MALS verified)

SKU: orb3032202

Description

ALK-7, also known as ACVR1C , is a Type I receptor for the TGF-beta family of signaling molecules. Upon ligand binding, it initiates intracellular signaling by phosphorylating cytoplasmic SMAD transcription factors. These activated SMADs then translocate to the nucleus to regulate gene expression, either directly or in complex with other transcription factors.

Images & Validation

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Application Notes	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 11.6 kDa. The protein migrates as 19-33 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

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Expression System	HEK293
Target	ALK-7
Reactivity	Monkey
Tag	C-10×His
Molecular Weight	11.6 kDa
Expression Region	Gly 25 - Glu 113
Purity	90%
Conjugation	Unconjugated

Storage & Handling

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Storage	-20°C to -70°C for 12 months in lyophilized state;. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower
Form/Appearance	Powder
Buffer/Preservatives	20 mM Tris, 150 mM NaCl, pH 7.5
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

ALK-7

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