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RO7567132 Antibody

SKU: orb2950022

Description

RO7567132 (FAP-LTBR) is a bispecific antibody that locally agonizes LTBR and antagonizes FAP within tumors, promoting tertiary lymphoid structure (TLS) formation while minimizing systemic effects. Preclinical studies in mouse models of breast and colorectal cancer demonstrate its ability to enhance immune infiltration and inhibit tumor growth, particularly in combination with anti-PD-L1 therapy.

Research Area

Cell Biology

Images & Validation

Key Properties

Antibody TypeInhibitor Antibody
ClonalityRecombinant
TargetTNF
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

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RO7567132 Antibody (orb2950022)

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