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Sabialimon P

SKU: orb2665384

Description

Sabialimon P (compound 16), with an IC50 of 18.12 μM, functions as a NO release inhibitor and exhibits anti-inflammatory properties. It effectively diminishes the secretion of TNF-α, iNOS, IL-6, and NF-κB, and suppresses the expression of COX-2 and NF-κB/p65 in LPS-induced RAW264.7 cells.

Research Area

Immunology & Inflammation, Neuroscience, Signal Transduction

Images & Validation

Key Properties

CAS Number2267333-96-8
MW486.73
FormulaC31H50O4
SMILESC(OC)(=O)[C@]12[C@](C=3[C@@](C)(CC1)[C@@]4(C)[C@](CC3)([C@]5(C)[C@@](CC4)(C(C)(C)[C@@H](O)C[C@@H]5O)[H])[H])(CC(C)(C)CC2)[H]
TargetNF-κB,COX,NO Synthase

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

Sabialimon P (orb2665384)

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