Secoisolariciresinol

SKU: orb1297211

Description

Research Area

Cell Biology

Images & Validation

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Key Properties

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CAS Number	29388-59-8
MW	362.42
Purity	99.65%
Formula	C₂₀H₂₆O₆
SMILES	COc1cc(C[C@@H](CO)[C@H](CO)Cc2ccc(O)c(OC)c2)ccc1O
Target	TNF
Solubility	DMSO:30 mg/mL (82.78 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (5.52 mM)

Bioactivity

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In Vitro

The effects of SECOs o the regulation of 3T3-L1 adipocytes, and identifie the structure-activity relationships. Optically active SECO and meso-SECO were tested for their effects on lipid metabolism in 3T3-L1 adipocytes. (-)-SECO accelerated adiponectin production of 3T3-L1 adipocytes. On the other hand (+)- and meso-SECO suppresse the production of adiponectin. In addition, triglyceride (TG) accumulation in 3T3-L1 adipocytes was significantly suppressed by All three SECOs tested here, as was 17beta-estradiol, whe the SECOs were added to the medium during induction of 3T3-L1 preadipocytes to adipocytes. Especially, (-)-SECO strongly reduced TG accumulatio

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Disclaimer	For research use only

Alternative Names

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Secoisolariciresinol, TNF-α, Inhibitor, inhibit

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Compound Identifiers

PubChem CID

65373 ↗

Key Properties

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No computed properties available.

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