Semapimod tetrahydrochloride

SKU: orb1694480

Description

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	164301-51-3
MW	890.74
Purity	99.80%
Formula	C₃₄H₅₆Cl₄N₁₈O₂
SMILES	Cl.Cl.Cl.Cl.C\C(=N/NC(N)=N)c1cc(NC(=O)CCCCCCCCC(=O)Nc2cc(cc(c2)C(\C)=N\NC(N)=N)C(\C)=N\NC(N)=N)cc(c1)C(\C)=N\NC(N)=N
Target	Interleukin,TLR,MAPK,TNF,p38 MAPK
Solubility	DMSO:1 mg/mL (1.12 mM);H2O:1 mg/mL (1.12 mM)

Bioactivity

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In Vivo	In Male OZ rats, Semapimod tetrahydrochloride (5 mg/kg; i.p.; once daily for 2 weeks) restored endothelium-dependent vasorelaxatio.

Storage & Handling

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Storage	keep away from direct sunlight,keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Disclaimer	For research use only

Alternative Names

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MAPK, CPSI-2364 tetrahydrochloride, Semapimod, TLR4, TLR6

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Compound Identifiers

PubChem CID

9554199 ↗

Key Properties

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No computed properties available.

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