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Silvestrol

SKU: orb1706633

Description

Silvestrol is a potent and selective inhibitor of eukaryotic initiation factor 4A (eIF4A), disrupting cap-dependent translation. This activity induces both autophagy and caspase-dependent apoptosis, making it a valuable tool for studying oncology, translational control, and cell death mechanisms in vitro and in vivo cancer models.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number697235-38-4
MW654.66
FormulaC34H38O13
SMILESCO[C@@H]1OC[C@@H](O[C@H]1Oc1cc2O[C@]3([C@@H]([C@H]([C@@H](O)[C@@]3(O)c2c(OC)c1)C(=O)OC)c1ccccc1)c1ccc(OC)cc1)[C@H](O)CO
TargetApoptosis,Autophagy,PERK,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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Silvestrol (orb1706633)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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