SpeB Protease Protein

SKU: orb1184789

Description

SpeB is derived from Streptococcus pyogenes. It is an important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. It also cleaves human IL1B precursor to form biologically active IL1B and can induce apoptosis in human monocytes and epithelial cells in vitro, reduces phagocytic activity in monocytic cells. Thus, it may play a role in bacterial colonization, invasion, and inhibition of wound healing.

Images & Validation

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Key Properties

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Expression System	E. coli
Target	SpeB
Reactivity	Bacteria
Tag	Native
Conjugation	Unconjugated

Storage & Handling

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Storage	-70°C
Form/Appearance	Liquid
Expiration Date	6 months from date of receipt.
Dry Ice Shipping	Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
Disclaimer	For research use only

Alternative Names

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Streptopain,Exotoxin type B,Streptococcal cysteine proteinase

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Quick Database Links

Gene Symbol

SpeB

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