Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Tacrine

SKU: orb1306361

Description

Tacrine is a centrally acting acetylcholinesterase inhibitor used as a cholinergic agonist in research. It is applied in studies of Alzheimer's disease, involving both in vitro enzyme assays and in vivo models to investigate cognitive enhancement and cholinergic mechanisms.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number321-64-2
MW198.26
Purity99.94% (May vary between batches)
FormulaC13H14N2
SMILESNc1c2CCCCc2nc2ccccc12
TargetAChR,Cholinesterase (ChE)
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (10.09 mM);H2O:Insoluble;DMSO:55 mg/mL (277.41 mM)

Bioactivity

Target IC50
AChE:109 nM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Cholinergic, Cholinesterase (ChE), CS 12602, CS12602, CS-12602, Alzheimer's disease, hepatotoxicity, Inhibitor, inhibit, Tacrine, Tacrinum, Tetrahydroaminocrine

Similar Products

  • Torilolone [orb1681559]

    13018-09-2

    252.35

    C15H24O3

    5 mg
  • AChE-IN-9 [orb1744329]

    609.63

    C30H35N5O9

    50 mg, 100 mg, 25 mg
  • 6,9-Dichloro-1,2,3,4-tetrahydroacridine [orb1694153]

    5396-25-8

    252.139

    C13H11Cl2N

    25 mg, 250 mg, 50 mg, 100 mg
  • Tacrine hydrochloride [orb1704785]

    1684-40-8

    234.73

    C13H15ClN2

    1 g, 5 g
  • bis(7)-Tacrine [orb1704896]

    224445-12-9

    565.63

    C33H42Cl2N4

    10 mg, 5 mg, 100 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 ml x 10 mM (in DMSO)
$ 80.00
5 mg
$ 80.00
10 mg
$ 90.00
25 mg
$ 140.00
50 mg
$ 180.00
100 mg
$ 240.00
500 mg
$ 440.00
DispatchUsually dispatched within 3-5 working days
Bulk Enquiry