Taurohyodeoxycholic acid

SKU: orb1984935

Description

Taurohyodeoxycholic acid (THDCA) is a bile acid that plays a key role in regulating the hepatic inflammatory microenvironment.THDCA reduces the expression of TNF-α and IL-6 and inhibits the development of hepatocellular carcinoma (HCC). It is able to inhibit non-alcoholic fatty liver disease and regulate bile acid metabolism in combination with astragalus polysaccharides: it reduces CD36 expression in the liver and decreases hepatic lipid accumulation by up-regulating CYP7B1 and down-regulating CYP7A1.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research

Images & Validation

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Key Properties

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CAS Number	2958-04-5
MW	499.7
Purity	99.38%
Formula	C₂₆H₄₅NO₆S
SMILES	C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCC(NCCS(=O)(=O)O)=O)C)(CC4)[H])[H])(C[C@H](O)[C@@]1(C[C@H](O)CC2)[H])[H])[H]
Target	Cytochromes P450,TNF,Endogenous Metabolite,IL Receptor

Storage & Handling

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Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Disclaimer	For research use only

Alternative Names

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Taurohyodeoxycholic acid, Taurohyodeoxycholic Acid MaxSpec® Standard

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Gene Symbol

Cytochromes P450,TNF,Endogenous Metabolite,IL Receptor

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