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Tesirine

SKU: orb2279239

Description

MP-PEG8-VA-PABC-PBD Dimer is a drug-linker conjugate designed for antibody-drug conjugates (ADCs). Its PBD dimer payload acts as a potent DNA alkylating agent, inhibiting DNA replication. This compound is used in cancer research for developing ADCs and has been evaluated in both in vitro cytotoxicity assays and in vivo xenograft models.

Research Area

Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1595275-62-9
MW1496.65
FormulaC75H101N9O23
SMILES[H][C@@]12CC(C)=CN1C(=O)c1cc(OC)c(OCCCCCOc3cc4N([C@@H](O)[C@]5([H])CC(C)=CN5C(=O)c4cc3OC)C(=O)OCc3ccc(NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN4C(=O)C=CC4=O)C(C)C)cc3)cc1N=C2
TargetDrug-Linker Conjugates for ADC,DNA Alkylator/Crosslinker,PROTAC Linker

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

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1 mg
$ 3,470.00
5 mg
$ 6,940.00
DispatchUsually dispatched within 5-10 working days
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