Wnt/β-catenin agonist 4

SKU: orb1689227

Description

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

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Key Properties

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CAS Number	912784-79-3
MW	314.31
Purity	99.96%
Formula	C₁₆H₁₅FN₄O₂
SMILES	Fc1ccc(cc1)-c1cc(no1)C(=O)NCCCn1ccnc1
Target	Wnt/beta-catenin
Solubility	DMSO:112.5 mg/mL (357.93 mM)

Bioactivity

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In Vitro

Wnt/β-catenin agonist 4, identified also as Derivative 83, demonstrates significant biological activity by enhancing ALP (alkaline phosphatase) activity by 2848% during the differentiation of the ST2 cell line into osteoblasts at a concentration of 11 μM over 4 days. Additionally, at a concentration of 120 μM for 24 hours, it exhibits a 1049% increase in β-catenin activity in HEK293 and SW480 cells.

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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βcatenin, Wnt/β-catenin, Wnt/b-catenin, Wnt/betacatenin, Wnt, betacatenin, beta-catenin, bcatenin

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Compound Identifiers

PubChem CID

16003392 ↗

Key Properties

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No computed properties available.

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