2-Hydroxychalcone

SKU: orb1299329

Description

2-Hydroxychalcone

Research Area

Cell Biology, Infectious Disease & Virology, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	644-78-0
MW	224.25
Purity	99.60%
Formula	C₁₅H₁₂O₂
SMILES	OC1=C(\C=C\C(=O)C2=CC=CC=C2)C=CC=C1
Target	Apoptosis,Bcl-2 Family,Parasite,NF-κB
Solubility	DMSO:22.5 mg/mL (100.33 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.92 mM)

Bioactivity

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In Vitro	2 hydroxychalcone induced apoptosis by Bcl-2 downregulation.?2 hydroxychalcone and xanthohumol exerted more potent inhibitory effects o the proliferation, MMP-9 expression and invasive phenotype of MDA-MB-231 than chalcon. Read more...

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Disclaimer	For research use only

Alternative Names

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TNBC, 2 Hydroxychalcone, 2-(2-Hydroxybenzal)Acetophenone, 2Hydroxychalcone, 2-Hydroxychalcone, Bcl-2 Family, Apoptosis, Inhibitor, inhibit, NFkB, NF-kB, NF-κB, NFκB, Nuclear factor-kappaB, Nuclear factor-κB

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Compound Identifiers

PubChem CID

5367146 ↗

Key Properties

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No computed properties available.

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