Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Itacitinib

SKU: orb1303457

Description

Itacitinib

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number1334298-90-6
MW553.51
Purity96.40% (May vary between batches)
FormulaC26H23F4N9O
SMILESFc1c(ccnc1C(F)(F)F)C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
TargetJAK
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.61 mM);DMSO:150 mg/mL (271 mM)

Bioactivity

In Vivo
Itacitinib (INCB039110) produced significant improvements in sPGA, demonstrating proof of concept in chronic plaque psoriasis.
In Vitro
Itacitinib is an inhibitor of the Janus kinases (JAKs) with selectivity for JAK1.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Inhibitor, Janus kinase, JAK1, JAK, Itacitinib, inhibit, INCB 039110, INCB039110, INCB-039110, INCB 39110, INCB39110, INCB-39110

Similar Products

  • Itacitinib adipate [orb1709391]

    1334302-63-4

    699.66

    C32H33F4N9O5

    2 mg
  • Itacitinib [orb1226524]

    >98% (HPLC)

    1334298-90-6

    553.5142

    C26H23F4N9O

    10 mg, 25 mg, 50 mg, 100 mg, 2 mg, 500 mg, 1 g, 5 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

2 mg
$ 110.00
5 mg
$ 160.00
1 ml x 10 mM (in DMSO)
$ 180.00
10 mg
$ 230.00
25 mg
$ 390.00
50 mg
$ 610.00
100 mg
$ 870.00
DispatchUsually dispatched within 3-5 working days
Bulk Enquiry