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Wnt/β-catenin activator 1

SKU: orb2944513

Description

Compound 5m is a potent, orally bioavailable small molecule activator of the Wnt/β-catenin pathway. It inhibits adipocyte proliferation and differentiation in vitro (IC50 = 330 nM in 3T3-L1 cells) and demonstrates anti-adipogenic and anti-dyslipidemic effects in high-fat diet-fed hamster models.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

MW382.43
FormulaC26H19FO2
TargetWnt/beta-catenin

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information