Wnt pathway activator 1

SKU: orb1307606

Description

Wnt pathway activator 1 is a highly potent small molecule Wnt/β-catenin signaling agonist, exhibiting an IC50 of 28-29 nM. It is utilized in research exploring hair follicle regeneration and has shown potential in preclinical models for androgenetic alopecia. This compound is a valuable tool for both in vitro and in vivo studies of Wnt pathway biology.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

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Key Properties

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CAS Number	1360540-81-3
MW	296.32
Purity	99.94%
Formula	C₁₈H₁₆O₄
SMILES	O=C(CCC(=O)c1ccc2OCCOc2c1)c1ccccc1
Target	Wnt/beta-catenin
Solubility	10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (8.44 mM);DMSO:60 mg/mL (202.48 mM)

Bioactivity

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Target IC50	Wnt:28-29 nM

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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beta-catenin, betacatenin, bcatenin, inhibit, Inhibitor, βcatenin, Wnt/β-catenin, Wnt, Wnt/b-catenin, Wnt/betacatenin, Wnt pathway activator 1, Wnt pathway activator1, Wnt pathway activator-1

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Compound Identifiers

PubChem CID

56837361 ↗

Key Properties

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No computed properties available.

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