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RORγt Inverse agonist 3

SKU: orb1708652

Description

RORγt Inverse agonist 3 is a potent, selective, and orally bioavailable inverse agonist for the RORγ and RORγt receptors, with EC50 values of 0.22 µM and 0.15 µM, respectively. This small molecule is a valuable research tool for investigating Th17 cell biology and autoimmune diseases in both cellular and animal models.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number2364429-77-4
MW616.56
FormulaC29H31Cl2N5O4S
SMILESCNC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(Cl)c(COc2cccc3c(cc(nc23)C(C)C)-c2cncn2C)c1Cl
TargetROR,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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RORγt Inverse agonist 3 (orb1708652)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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